Protein Purification Reagents and Kits
Cell Biolabs Inc Urinary Creatinine Assay Kit, 192 assays
Creatine and p-creatine are converted non-enzymatically to creatinine, which enters the blood and is excreted by the kidneys via glomerular filtration. The analysis of creatinine in serum and urine is an important clinical test for renal disease and dysfunction. Creatinine is removed from plasma by the glomerulus and then excreted in the urine without any appreciable resorption by the tubules. This “creatinine clearance” from the body is used to measure glomerular filtration rates. Cell Biolabs’ Urinary Creatinine Assay Kit is based on the Jaffe reaction, produces an orange-red color complex that can be measured with a standard spectrophotometric plate reader. Each kit provides sufficient reagents to perform up to 192 assays, including blanks, creatinine standards and unknown urine samples. High concentrations of ascorbic acid, uric acid, glucose, ketones and cephalosporin antibiotics may interfere with the assay causing falsely high values.
Cayman Chemical 1012 ZConjUGated LInole 25mg
An isomer of linoleic acid; has been found in bovine milk products; binds to PPARα (IC50 = 200 nM) and activates PPARα in a reporter assay using COS-1 cells expressing the mouse receptor; inhibits stearoyl-CoA desaturase activity in mouse liver microsomes and TRAP activity in media from primary human CD14+ monocytes; induces apoptosis in LoVo and HT-29 colon cancer cells at 100 µM; reduces epididymal, perirenal, and subcutaneous white adipose tissue weights in hamsters fed an atherogenic diet
Abcam ChIP Kit Magnetic - One Step, 96 Tests
Abcam's ChIP Kit Magnetic - One Step (ab156907) is a complete set of optimized buffers and reagents to carry out a successful chromatin immunoprecipitation for the selective enrichment of a chromatin fraction containing specific DNA sequences from isolated chromatin, in order to investigate the interaction between proteins and DNA in a cell.
The product is subject to the following: Abcam Restricted Use Statement
Bioworld Protoplast Isolation Kit, 20 Prep(s)
Protoplast Isolation KitProtoplast isolation kit is used to the isolation of protoplast from plant tissue. Contents: all necessary enzymes, buffers and reagents to perform isolation of protoplasts.
Cayman Chemical GlutathIon PRoxIdase asy 480
GPX catalyzes the reduction of hydroperoxides, including H2O2, using reduced glutathione and thereby functions to protect the cell from oxidative damage. Cayman’s Glutathione Peroxidase Assay measures GPX activity indirectly by a coupled reaction with GR. Oxidized GSSG, produced upon reduction of an organic hydroperoxide by GPX, is recycled to its reduced state by GR and NADPH. The oxidation of NADPH to NADP+ is accompanied by a decrease in absorbance at 340 nm. The rate of decrease in the absorbance at 340 nm is directly proportional to the GPX activity in the sample. Cayman’s GPX Assay can be used to measure all of the glutathione-dependent peroxidases in plasma, erythrocyte lysates, tissue homogenates, and cell lysates.
Cayman Chemical 1012 ZConjUGated LInole 10mg
An isomer of linoleic acid; has been found in bovine milk products; binds to PPARα (IC50 = 200 nM) and activates PPARα in a reporter assay using COS-1 cells expressing the mouse receptor; inhibits stearoyl-CoA desaturase activity in mouse liver microsomes and TRAP activity in media from primary human CD14+ monocytes; induces apoptosis in LoVo and HT-29 colon cancer cells at 100 µM; reduces epididymal, perirenal, and subcutaneous white adipose tissue weights in hamsters fed an atherogenic diet
Abcam Ciglitazone, PPARgamma agonist, 50MG
MW 333.4 Da, Purity >98%. Selective PPARγ agonist (EC₅₀ = 3 μM). Shows antidiabetic and antineoplastic activity. Induces cell cycle arrest and apoptosis. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Vector Biolabs v-myc myelocytomatosis viral oncogene homolog 1 lung carcinoma derived Adenovirus (Ad-L-Myc)
Ready to use in vivo grade AAV and Adenovirus Ready to use in vivo grade AAV and Adenovirus pre synthesized DNA vector High titer viral vectors 1/EA
AdipoGen HES1 human rec His
Protein. Human HES1 aa 2-280 is fused at the N-terminus to a His-tag. Source E. coli. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >90% SDS-PAGE. bHLH proteins are essential for neurogenesis, myogenesis, hematopoiesis and sex determination. HES1 Hairy and Enhancer of Split 1 is a basic Helix-Loop-Helix bHLH transcriptional repressor regulated by the Notch pathway and expressed in various tissues. HES1 is well known in development of different tissues, particularly endoderm derived endocrine organs like pancreas and neuroendocrine cells of lung. HES1 controls normal development by regulating proliferation and differentiation and so cell fate. Notch signaling plays both oncogenic and tumor suppressor roles depending on cell type. In contrast to T cell acute lymphoblastic leukemia ALL, where Notch activation promotes leukemogenesis, induction of Notch signaling in B cell ALL B-ALL leads to growth arrest and apoptosis.
AdipoGen ANGPTL8 msFc hrec
Protein. Mouse ANGPTL8 Betatrophin 22-198 is fused at the C-terminus to the Fc portion of human IgG1. Source HEK 293 cells. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS 0.02% CHAPS. Purity >90% SDS-PAGE. ANGPTL8 Angiopoietin-like protein 8 RIFL Lipasin Betatrophin is a newly discovered secreted protein of 198 aa that was proposed to promote beta cell proliferation and improve glucose tolerance in mice. ANGPTL8 may also function in inhibition of lipase activity and on serum triglyceride regulation. ANGPTL8 is expressed in the liver and in white and brown adipose tissue of mice. In humans, ANGPTL8 is found to be predominantly expressed in the liver. ANGPTL8 levels are reduced by fasting and are elevated upon insulin resistance and during pregnancy. ANGPTL8, according to preliminary data could bind to the macrophage receptor Marco and also to RTN4R, a neuronal receptor.
AdipoGen KillerTRAIL Soluble hrec
Protein. The extracellular domain of human TRAIL aa 95-281 is fused at the N-terminus to a His-tag and a linker peptide. Source E. coli. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Liquid. In 20mM HEPES, pH 7.4, 150mM NaCl, 0.005% Tween 20, 1% sucrose, 1mM DTT. Binds to human and mouse TRAIL receptors and osteoprotegerin OPG. Purity >98% SDS-PAGE. TNF-related apoptosis-inducing ligand TRAIL Apo2LCD253 TNFSF10 is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor TNF superfamily of cytokines TRAIL can be cleaved at the cell surface by metalloproteases to form a soluble molecule. Active TRAIL forms trimers and specifically binds to five distinct receptors TRAIL-R1 DR4 Apo2CD261 TNFRSF10A, TRAIL-R2 DR5 KILLER TRICK2ATRICK2B CD262 TNFRSF10B, TRAIL-R3 DcR1LIT TRID CD263 TNFRSF10C, TRAIL-R4 DcR2TRUNDD CD264 TNFRSF10D, and osteoprotegerin OPG OCIF TNFRSF11B.
Biotium Cytokeratin 18(DA7), CF647 conjugate, 0.1mg/mL
This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower flu
Arbor Assays Thiol Fluorescent Detection Kit (1 Plate)
The DetectX Thiol Fluorescent Detection Kit allows users to accurately determine the extent of free thiol content in samples using a proprietary substrate, ThioStar, that is converted to a brightly fluorescent product upon reaction with thiols in the sample.